Information and Nutrition
Historically, most laminitis cases were thought to occur as a result of an inflammatory response, from over consumption of pasture and other feeds which are high in soluble carbohydrates, leading to a disruption to the hindgut microbiome, which caused the release of endotoxins, together with the excessive production of free radicals from oxidative processes. The actual physiological responses which lead to laminitis are still unclear, but it is thought that the inflammatory response and the high level of damaging free radicals produced by oxidation during the inflammatory response ultimately affect blood supply to the feet. This restriction of blood to the feet causes damage and death to the laminae, resulting in pain and lameness, and in severe cases, rotation of the pedal bone.
Excessive concussion of the feet (working on hard ground), retained placenta in broodmares, systemic infections and supporting limb (following an injury) laminitis are also all thought to result in laminitis as a result of Systemic Inflammatory Response Syndrome (SIRS) - Laminitis caused by inflammation and resulting oxidative damage.
However, recent studies have reported that a high proportion of laminitis cases are now thought to occur as a result of Endocrine or hormonal dysfunction.
These hormone imbalances can occur either as a result of PPID (Pars Pituitary Intermedia Dysfunction, commonly known as Cushings Disease), or a range of syndromes referred to as Equine Metabolic Syndrome or EMS. These disorders are characterised by, amongst other symptoms, insulin resistance (IR) and maybe be genetic in origin, as there seems to be a high incidence in Native ponies and some draft breeds. Again, it is not yet fully clear why higher than normal insulin levels can result in laminitis, but one theory is that insulin resistance may be associated with high levels of key proteins which cause vasoconstriction or narrowing of blood vessels in the feet. This is thought to result in narrowing and stretching of the lamellar cells over a period of time, before symptoms of pain and lameness become obvious to the owner – unlike SIRS laminitis, which is usually rapid in onset.
Lamigard TRT XXXTreme Solution contains a potent blend of key antioxidants and other supporting nutrients and plant extracts to help in long term nutritional management of horses and ponies prone to both SIRS laminitis and those with endocrine dysfunction.
What are the benefits of Lamigard XXXtreme Solution?
Melon Pulp is a natural source of key antioxidant enzymes.
Magnesium also plays a key role in helping to support a normal antioxidant and inflammatory response.
Folic Acid plays a key role in nitric oxide generation, which is important for vasodilation -helping to keep blood vessels open in the feet.
Vitamin E is one of the most important antioxidant vitamins to help neutralize damaging free radicals and support the immune system.
Milk Thistle and Marshmallow are important plant-based antioxidant also help to support the liver.
Additional plant extracts (including natural sources of resveratrol) to support healthy blood vessels and a normal inflammatory response.
A complementary feed for horses and ponies, to support a healthy metabolism as part of a balanced diet.
Directions for feeding: Horses and large ponies: 30 ml twice daily for 7 days, followed by 30 ml once daily for a further 7 days. Thereafter, 15 ml per day for maintenance. Maximum 60 ml per day.
Smaller ponies: 20ml twice daily for 7 days, followed by 20 ml once daily for 7 days. Thereafter 10 ml per day for maintenance. Maximum 40 ml per day.
Key Ingredients per 30 ml Serving
Milk Thistle extract 2000mg
Melon Juice (antioxidant) 1.5g
Folic Acid 300mg
Vitamin E 300mg
Marshmallow extract 1000mg
Nutritional additives/kg: Vitamins: Vitamin E (3a700) 10,000mg, Folic Acid (3a316) 10,000mg
Sensory additives: 2b Milk Thistle Extract 66,700mg, Althaea officinalis (Marshmallow) extract 33,330mg
Composition: Water, Magnesium chloride, Melon Pulp